Illumina Inc. ILMN
AI-generated report · not investment advice · figures extracted automatically; please verify against the linked original more
Business Model#
What the company does and how it earns its money; written AI-editorially, exclusively from the company's original reports, without any assessment of our own.
Illumina is a life sciences company that develops and commercializes next-generation sequencing and array-based solutions for genetic analysis. Its revenue is derived from instruments, consumables (including flow cells, reagents, and library preparation kits), and services, with consumables providing recurring revenue through an installed-base attach model tied to platforms such as NovaSeq X. The company serves research institutions, academic laboratories, pharmaceutical and biotechnology companies, clinical diagnostics providers, and government entities globally. Through the SomaLogic acquisition, Illumina has extended its addressable market into proteomics, broadening its portfolio toward a multiomics platform strategy.
Current Status#
Summary of the most recent reporting period: core figures, drivers and management statements; written editorially from the current original report, every figure backed by a source number.
Price & Chart#
Interactive price chart (TradingView) and the trend of key figures from the core tables. The price chart loads only after a click; at that point a connection to TradingView is established.
Daily candles with news and earnings markers. Loads only on click.
Share-Price Drivers#
Factors the company itself names as material for its business development (IR-based); reproduced neutrally, no price forecast and no assessment of our own.
NovaSeq X remains the central platform being expanded with new workflow and multiomics capabilities, and its transition drives high-margin consumable revenue as the installed base scales (31, 33, 6e0b86c04d)
NovaSeq X launched 2023 and still actively developed through 2026-Q2 with workflow and multiomics enhancements; total revenue rose to 1,159 in 2026-Q2 from 1,059 a year earlier (31, 33, 133)
SomaLogic proteomics acquisition closed, plus Illumina Protein Prep, Single Cell 3' RNA Prep, Constellation mapped-read and spatial solutions launched 2025 (34, 30, 26)
TSO 500 v2 launched 2025-Q2, TSO Comprehensive approved in Japan, and pharma development partnerships added 2025-Q3 (24, 26)
Adjusted operating income and FCF held firm (2026-Q2 FCF 162 on 260 adj. operating income); change flags show growth accelerating and profitability improving (133, change flags)
2030 term notes issued 2025-11 and a 2026 repurchase program authorized 2026-04; net debt 451 at 2026-Q2 (34)
No guidance flag reported alongside the latest quarter (change flags)
Sector trend: Sequencing demand KPIs are firming as instrument-platform expansion lifts consumables pull-through and revenue re-accelerates toward high-single-digit year-over-year growth, while adjusted operating margins and free cash flow hold steady (133, 34).
Event Timeline#
This timeline collects the material events from the original reports: guidance changes, revenue and margin signals, strategy shifts, product and M&A announcements. Events are grouped by quarter (most recent first); the grey tag before each event names the event type, the date is the publication date of the source. Management quotes open the quarter block as direct quotes. Per quarter we show the three most defining events; more can be expanded per quarter, older years are collapsed. Every event carries its source as a superscript, clickable number.
2026 · 6 events
2026-Q2 · Apr – Jun 2026
Q2 revenue up 9.5% to $1.16 billion; ROW organic revenue growth of 8.1% excluding currency and acquisitions 33
Non-GAAP operating margin declined to 22.5% in Q2 2026 from 23.8% in Q2 2025 33
FY2026 revenue guidance raised to $4.60-$4.64 billion; non-GAAP diluted EPS guidance raised to $5.30-$5.40 33
2026-Q1 · Jan – Mar 2026
Acquired SomaLogic for $460 million to expand presence in proteomics market and advance multiomics strategy 32
Q1 revenue up 4.8% to $1.09 billion driven by NovaSeq X high-throughput consumables and instruments demand 31 32
FY2026 revenue guidance raised to $4.52-$4.62 billion; non-GAAP diluted EPS guidance raised to $5.15-$5.30 31
2025 · 18 events
FY2025 · Jan – Dec 2025
Operating income turned positive for the first time after 2 negative fiscal years (-833.0 to +807.0 USDm). 28
Net income turned positive for the first time after 2 negative fiscal years (-1223.0 to +850.0 USDm). 28
2025-Q4 · Oct – Dec 2025
Q4 2025 revenue $1.16 billion, up 5% reported (4% constant currency) from Q4 2024; ex-China revenue up 8% reported and 7% constant currency 29
FY2026 revenue guidance of $4.5 billion to $4.6 billion, representing 4%–6% reported growth, including a 1.5%–2.0% contribution from the recently closed SomaLogic acquisition 29
Completed acquisition of SomaLogic from Standard BioTools for $350 million expanding multiomics portfolio with NGS-enabled proteomics; separately, MOFCOM lifted sequencing instrument export ban though Illumina remains on China's Unreliable Entities List 29
2025-Q3 · Jul – Sep 2025
Revenue $1.08 billion in Q3 2025, flat compared to Q3 2024 on both reported and constant currency basis, improving from first-half declines; nine-month revenue down 2% constant currency 26
Non-GAAP operating margin of 24.5% in Q3 2025; YTD gross margin improved to 66.3% from 65.3% in YTD 2024, partly reflecting removal of lower-margin GRAIL operations following the June 2024 spin-off 26 27
Launched BioInsight, a new business to accelerate technology and data-driven discovery initiatives 26
2025-Q2 · Apr – Jun 2025
Non-GAAP operating margin improved to 23.8% in Q2 2025 from 22.2% in Q2 2024 24
FY2025 constant currency revenue guidance raised to (2.5%) to (0.5%) decline and non-GAAP operating margin guidance raised to approximately 22%–22.5% 24
Definitive agreement to acquire SomaLogic and specified assets from Standard BioTools for $350 million in cash plus up to $75 million in milestone payments, expected to close H1 2026 24
2025-Q1 · Jan – Mar 2025
China added Illumina to Unreliable Entities List in February 2025 and prohibited sequencing instrument exports from March 2025, materially reducing Greater China revenue access for the year 23
Core Illumina revenue $1.04 billion, down 1% reported (flat constant currency) in Q1 2025; total revenue down 3% primarily due to removal of GRAIL contribution following the June 2024 GRAIL Spin-Off and decreased service and other revenue 22 23
Incremental $100 million cost reduction program implemented including workforce reductions and productivity measures to mitigate Greater China revenue and operating income impact 22
Operating cash flow reached 240.0 USDm vs 77.0 USDm in 2024-Q1 (×3.1). 131
2024 · 15 events
2024-Q4 · Oct – Dec 2024
FY2024 Core Illumina non-GAAP operating margin of 21.3% and Q4 2024 non-GAAP operating margin of 19.7%, reflecting sustained improvement in product mix and operational efficiency versus prior-year levels (20)
2024-Q3 · Jul – Sep 2024
GAAP net income of $705M in Q3 2024 versus net loss of $1,988M in Q2 2024; improvement driven by absence of Q2's $1,886M GRAIL impairment charges and recognition of $481M gain from European Commission's September 2024 withdrawal of its €432M fine – not reflecting recurring operational improvement (18, 126)
FY2024 Core Illumina revenue guidance lowered to approximately -3% from fiscal 2023, reflecting continued instrument demand weakness (17)
FY2024 Core Illumina non-GAAP operating margin guidance raised to 21%-21.5% and non-GAAP diluted EPS guidance raised to $4.05-$4.15 (17)
Operating income turned positive for the first time after 9 negative periods (-1637.0 to +244.0 USDm). 126
EBITDA turned positive for the first time after 4 negative periods (-1532.0 to +314.0 USDm). 126
2024-Q2 · Apr – Jun 2024
Core Illumina revenue declined 6% year-over-year to $1.09B in Q2 2024, driven by softer instrument demand in a constrained funding environment despite solid consumable sales (15)
FY2024 Core Illumina non-GAAP operating margin guidance raised to 20.5%-21%; non-GAAP diluted EPS guidance of $3.80-$3.95 introduced for the first time (15)
2024-Q1 · Jan – Mar 2024
Consolidated revenue declined 1% to $1,076M in Q1 2024; Core Illumina revenue down 2%, driven by fewer high-throughput and mid-throughput instrument shipments (14, 13)
Core Illumina non-GAAP operating margin expanded to 20.6% from 17.4% in Q1 2023, supported by favorable consumables mix and operational excellence cost savings (13)
European Commission approved GRAIL divestment plan in April 2024; Illumina on track to finalize divestiture terms by end of Q2 2024 (13)
Operating cash flow reached 77.0 USDm vs 10.0 USDm in 2023-Q1 (×7.7). 13
2023 · 15 events
2023-Q4 · Oct – Dec 2023
Q4 2023 revenue of $1,122 million increased 4% YoY, the strongest year-over-year growth quarter of fiscal 2023; full-year FY2023 revenue declined 2% to $4,504 million 11
FY2024 guidance issued: Core Illumina revenue approximately flat year-over-year, non-GAAP operating margin approximately 20% 11
2023-Q3 · Jul – Sep 2023
Q3 GAAP operating loss widened to $(754) million, including $712 million in GRAIL goodwill impairment and $109 million in intangible asset impairment charges 8 9
Retained advisors and preparing Form 10 filing for GRAIL divestiture in accordance with European Commission divestiture order 8
2023-Q2 · Apr – Jun 2023
Q2 2023 revenue of $1,176 million rose 1% YoY, recovering from Q1 2023's 11% year-over-year decline, and up 8% sequentially 6
Core Illumina non-GAAP operating margin declined to 7.0% from 12.2% in Q2 2022 due to NovaSeq X platform launch costs and lower manufacturing volumes 6
Three new independent directors named, Stephen MacMillan elected non-executive chair, and Charles Dadswell appointed Interim CEO 6
2023-Q1 · Jan – Mar 2023
Gross margin fell to 60.3% from 66.6% in Q1 2022, driven by lower manufacturing volumes and lower instrument margins from NovaSeq X launch 5
Q1 2023 revenue declined 11% YoY (9% constant currency) to $1,087 million, driven by lower sequencing consumables and instruments 5
Announced plan to reduce annualized run rate expenses by more than $100 million beginning later in 2023 4
Net income turned positive for the first time after 3 negative periods (-140.0 to +3.0 USDm). 113
EBITDA turned positive for the first time after 3 negative periods (-21.0 to +43.0 USDm). 113
Key Figures ($m)#
The company's core financial figures in three views, one below the other: fiscal years (as reported; after restatements the table shows the most recent filing version, marked), half-years (6-month basis, H2 = second half on its own) and quarters (3-month basis, not cumulative). Each row is one period, most recent first. Values with a dotted underline are clickable and show the raw value, the exact source location, the scale evidence and the source; derived values additionally show their formula and inputs. All values are extracted automatically from the filings; errors are possible; please verify decision-relevant figures yourself by clicking through to the linked original.
All figures serve only to support your own investment decision and are not a recommendation; the company's original reports are authoritative.
Fiscal years
| Period | Revenue | Op. income | Op. income (adj.) | Net income | EPS ($) | EPS adj. ($) | OCF | Source |
|---|---|---|---|---|---|---|---|---|
| FY2025 | 4,343 | 807 | 1,004 | 850 | 5.45 | 4.84 | 1,079 | 28 |
| FY2024 | 4,372 | -833 | 922 | -1,223 | -7.69 | 4.16 | 837 | 21 |
| FY2023 | 4,504 | -1,069 | 884 | -1,161 | -7.34 | 0.86 | 478 | 12 |
Quarters
| Period | Published | Revenue | Op. income | Op. income (adj.) | Net income | EPS ($) | EPS adj. ($) | FCF | Cash | Net Debt | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-Q2* | 2026-07-30 | 1,159 | 245 | 260 | 207 | 1.35 | 1.31 | 162 | 1,040 | 451 | 133 |
| 2026-Q1* | 2026-04-30 | 1,091 | 209 | 239 | 134 | 0.87 | 1.15 | 251 | 1,089 | 401 | 31 |
| 2025-Q4* | 2026-02-05 | 1,159 | 202 | 275 | 334 | 2.14* | 1.35 | 267 | 1,418 | 72 | 129 |
| 2025-Q3* | 2025-10-30 | 1,084 | 227 | 265 | 150 | 0.98 | 1.34 | 253 | 1,050 | -56 | 126 |
| 2025-Q2* | 2025-07-31 | 1,059 | 214 | 252 | 235 | 1.49 | 1.19 | 204 | 934 | 558 | 24 |
| 2025-Q1* | 2025-05-08 | 1,041 | 164 | 212 | 131 | 0.82 | 0.97 | 208 | 1,113 | 378 | 22 |
| 2024-Q4* | 2025-02-06 | 1,104 | 175 | 218 | 187 | 1.18* | 0.95 | 322 | 1,127 | 363 | 20 |
| 2024-Q3* | 2024-11-04 | 1,080 | 244 | 244 | 705 | 4.42 | 1.14 | 284 | 869 | 1,119 | 17 |
| 2024-Q2* | 2024-08-06 | 1,112 | -1,637 | 242 | -1,988 | -12.48 | 1.09 | 211 | 920 | 570 | 15 |
| 2024-Q1* | 2024-05-02 | 1,076 | -111 | 218 | -126 | -0.79 | 0.97 | 41 | 1,108 | 382 | 13 |
| 2023-Q4* | 2024-02-08 | 1,122 | -164 | 203 | -176 | -1.11* | 0.14 | 173 | 1,048 | 441 | 11 |
| 2023-Q3* | 2023-11-09 | 1,119 | -754 | 249 | -754 | -4.77 | 0.33 | 94 | 927 | 562 | 108 |
| 2023-Q2* | 2023-08-09 | 1,176 | -88 | 245 | -234 | -1.48 | 0.32 | 58 | 1,553 | 685 | 6 |
| 2023-Q1* | 2023-04-25 | 1,087 | -64 | 187 | 3 | 0.02 | 0.08 | -42 | 1,494 | 742 | 4 |
Balance Sheet & Cash Flow ($m)#
Point-in-time balance sheet items (e.g. cash, financial debt) and cash flow items (operating cash flow, investments/capex) per fiscal year, half-year and quarter. Balance sheet values are as of the period end, flow items cover the period. Derived values are marked and are calculated, for example, as: net debt = financial debt − cash; free cash flow = operating cash flow − capex; the click popover shows formula and inputs. All values are extracted automatically from the filings; errors are possible; please verify decision-relevant figures yourself by clicking through to the linked original.
Fiscal years
| Period | Published | Cash | Debt | Net Debt | D&A | OCF | Capex | FCF | Source |
|---|---|---|---|---|---|---|---|---|---|
| FY2025 | 2026-02-05 | 1,418 | 1,490 | 72 | 270 | 1,079 | 148 | 931 | 29 |
| FY2024 | 2025-01-14 | 1,127 | 1,490 | 363 | 354 | 837 | 128 | 709 | 19 |
| FY2023 | 2024-02-08 | 1,048 | 1,489 | 441 | 432 | 478 | 195 | 283 | 11 |
Quarters
| Period | Published | Cash | Debt | Net Debt | D&A | OCF | Capex | FCF | Source |
|---|---|---|---|---|---|---|---|---|---|
| 2026-Q2 | 2026-07-30 | 1,040 | 1,491 | 451 | 70 | 201 | 39 | 162 | 133 |
| 2026-Q1 | 2026-04-30 | 1,089 | 1,490 | 401 | 69 | 289 | 38 | 251 | 31 |
| 2025-Q4 | 2026-02-05 | 1,418 | 1,490 | 72 | 66 | 321 | 54 | 267 | 129 |
| 2025-Q3 | 2025-10-30 | 1,050 | 994 | -56 | 67 | 284 | 31 | 253 | 126 |
| 2025-Q2 | 2025-07-31 | 934 | 1,492 | 558 | 68 | 234 | 30 | 204 | 24 |
| 2025-Q1 | 2025-05-08 | 1,113 | 1,491 | 378 | 69 | 240 | 32 | 208 | 22 |
| 2024-Q4 | 2025-02-06 | 1,127 | 1,490 | 363 | 71 | 364 | 42 | 322 | 20 |
| 2024-Q3 | 2024-11-04 | 869 | 1,988 | 1,119 | 70 | 316 | 32 | 284 | 17 |
| 2024-Q2 | 2024-08-06 | 920 | 1,490 | 570 | 105 | 243 | 32 | 211 | 15 |
| 2024-Q1 | 2024-05-02 | 1,108 | 1,490 | 382 | 108 | 77 | 36 | 41 | 13 |
| 2023-Q4 | 2024-02-08 | 1,048 | 1,489 | 441 | 109 | 224 | 51 | 173 | 11 |
| 2023-Q3 | 2023-11-09 | 927 | 1,489 | 562 | 108 | 139 | 45 | 94 | 108 |
| 2023-Q2 | 2023-08-09 | 1,553 | 2,238 | 685 | 108 | 105 | 47 | 58 | 6 |
| 2023-Q1 | 2023-04-25 | 1,494 | 2,236 | 742 | 107 | 10 | 52 | -42 | 4 |
Revenue by Type (as of 2026-Q2 · USDm · 0/1)#
Revenue split by segment or product type, exactly as the company itself reports it. The basis is stated next to each value (3, 6 or 12 months); segment totals can deviate from group revenue (reconciliation/consolidation items). If the company changes its segment structure, older structures are kept in the expandable part. Rows in grey are no longer reported separately by the company; they show the last available figures and are never extrapolated.
| Segment | Since | Period | Basis | Revenue | Source |
|---|---|---|---|---|---|
| GRAIL | 2022-Q1 | 2024-Q1 | 3M | 27 | 14 |
Products & M&A (14/39 active+recent)#
Product announcements from the reports; market launches, approvals, partnerships; with first mention (date) and source. “Active/current” means: still mentioned in the most recent reports; what the company no longer mentions moves to the expandable part but is never deleted. Rows in grey are discontinued products.
| Product/Line | Since | Status | Source |
|---|---|---|---|
| NovaSeq X workflow and multiomics capabilities expansion | 2026-06 | Launched | 33 |
| 5-base solution (2x) | 2025-10 | Launched | 26 |
| TruSight Oncology pharmaceutical development partnerships | 2025-09 | Launched | 26 |
| Illumina Protein Prep | 2025-09 | Launched | 30 |
| Constellation mapped read technology (2×) | 2025-09 | Launched | 30 |
| BioInsight | 2025-09 | Launched | 26 |
| TruSight Oncology (TSO) Comprehensive approval from Japan's Ministry of Health, Labour and Welfare | 2025-06 | Launched | 24 |
| PromoterAI | 2025-06 | Launched | 24 |
| Spatial transcriptomics technology | 2025-03 | Launched | 22 |
| Illumina Single Cell 3' RNA Prep | 2025-01 | Launched | 30 |
| Billion Cell Atlas | 2025 | Launched | 29 |
| DRAGEN v4.4 software (2×) | 2024-06 | Launched | 24 |
| TruSight Oncology 500 ctDNA v2 launch (3×) | 2023-09 | Launched | 24 |
| 2030 Term Notes issuance (4×) | 2021-03 | Launched | 34 |
| UK Biobank proteomics pilot program | 2024-12 | Launched | 20 |
| TruSight Oncology expansion | 2024-12 | Launched | 20 |
| Regeneron collaboration and Truveta Genome Project investment | 2024-12 | Launched | 20 |
| NVIDIA collaboration for multiomic data analysis | 2024-12 | Launched | 20 |
| Updates on whole-genome sequencing, proteomics, and single-cell technology | 2024-09 | Launched | 17 |
| TSO Comprehensive with two companion diagnostics | 2024-09 | Launched | 17 |
| Bengaluru global capability center | 2024-09 | Launched | 17 |
| TruSight Oncology 500 HT high-throughput version expansion | 2024-06 | Launched | 15 |
| XLEAP-SBS chemistry on NextSeq 1000 and NextSeq 2000 Systems (2×) | 2024-03 | Launched | 15 |
| Illumina Complete Long Reads (ICLR) with Enrichment | 2024-03 | Launched | 13 |
| MiSeq i100 Series (2×) | 2024 | Launched | 27 |
| REACH/Galleri-Medicare study initiation | 2023-12 | Launched | 11 |
| Global Health Access Initiative launch | 2023-12 | Launched | 11 |
| Illumina Solutions Center in Bengaluru, India | 2023-09 | Launched | 8 |
| 25B flow cell (300-cycle kit) for NovaSeq X | 2023-09 | Launched | 8 |
| Convertible senior notes due August 15, 2023 | 2023-08 | Launched | 5 |
| PrimateAI-3D | 2023-06 | Launched | 6 |
| GRAIL SYMPLIFY study results (2×) | 2023-06 | Launched | 6 |
| DRAGEN 4.2 | 2023-06 | Launched | 6 |
| Illumina Connected Insights | 2023-03 | Launched | 4 |
| Illumina Complete Long Read Prep, Human | 2023-03 | Launched | 4 |
| Revolving Credit Agreement | 2023-01 | Stable | 32 |
| XLEAP-SBS sequencing chemistry launch (2×) | 2023 | Launched | 21 |
| NovaSeq X Plus launch (3×) | 2023 | Launched | 9 |
| NovaSeq X (2×) | 2023 | Launched | 31 |
M&A (22)#
All recorded acquisitions (purchases) and divestitures/exits with date, short description and source; deliberately including smaller transactions that summaries often miss. Purchase prices appear only where the company itself has disclosed them. Rows in grey are cancelled transactions; the cancellation date is shown in the row.
Acquisitions
| Transaction / stake | Date | Type | Source |
|---|---|---|---|
| SomaLogic acquisition from Standard BioTools (2×) | 2025-06 | Completed | 28 |
| Tempus partnership for clinical adoption | 2025-03 | Completed | 22 |
| Broad Institute flagship collaboration project | 2025-03 | Completed | 22 |
| Broad Clinical Labs collaboration | 2025-03 | Completed | 22 |
| SomaLogic acquisition | 2025 | Completed | 34 |
| 2026 Repurchase Program authorization (3×) | 2024-08 | Completed | 34 |
| Fluent Biosciences acquisition | 2024-06 | Completed | 15 |
| Collaboration with AstraZeneca for GRAIL risk classification test | 2024-03 | Completed | 13 |
| Janssen collaboration on molecular residual disease assay | 2023-12 | Completed | 11 |
| GRAIL Galleri pilot expansion with Point32Health | 2023-09 | Completed | 8 |
| GRAIL Galleri collaboration with HCA Healthcare | 2023-09 | Completed | 8 |
| Pillar Biosciences partnership | 2023-06 | Completed | 6 |
| Alliance for Genomic Discovery expansion (2×) | 2023-06 | Completed | 11 |
| Partnership with Henry Ford Health for genomic testing in cardiovascular disease | 2023-03 | Completed | 4 |
| Partnership with FirstHealth of the Carolinas for Galleri offering | 2023-03 | Completed | 4 |
| John Hancock expanded Galleri access for Vitality PLUS program | 2023-03 | Completed | 4 |
| Expanded partnership with Providence Health System for Galleri | 2023-03 | Completed | 4 |
| Expanded partnership with Myriad Genetics for TSO 500 HRD oncology testing | 2023-03 | Completed | 4 |
Divestitures / exits
| Transaction / stake | Date | Type | Source |
|---|---|---|---|
| GRAIL spin-off (2×) | 2024-06 | Divested | 30 |
| GRAIL acquisition | 2023-12 | Divested | 14 |
| European Commission fine for GRAIL acquisition | 2023-07 | Divested | 6 |
| Potential GRAIL divestment | 2023-06 | Divested | 7 |
Reported KPIs (as disclosed) (199)#
Figures the company discloses itself in addition to the standard financials; order intake, recurring revenue, user or unit counts, adjusted measures. These “story KPIs” usually slip through standard databases; here they are collected as reported, with no calculation of our own. Important: the definition comes from the company itself and can differ from firm to firm; period and source are stated next to every value.
| Date | Period | KPI | Value / change | Source |
|---|---|---|---|---|
| 2026-07-31 | 2026-Q2 | total cash and investments | $1,168 | 34 |
| 2026-07-31 | 2026-Q2 | short-term investments | $128 | 34 |
| 2026-07-31 | 2026-Q2 | revolving credit facility | $750 | 34 |
| 2026-07-31 | 2026-Q2 | operating margin YTD 2026 | 20.2% | 34 |
| 2026-07-31 | 2026-Q2 | operating margin YTD 2025 | 18.0% | 34 |
| 2026-07-31 | 2026-Q2 | gross margin YTD 2026 | 66.2% | 34 |
| 2026-07-31 | 2026-Q2 | gross margin YTD 2025 | 65.6% | 34 |
| 2026-07-31 | 2026-Q2 | gross margin Q2 2026 | 66.4% | 34 |
| 2026-07-31 | 2026-Q2 | gross margin Q2 2025 | 65.6% | 34 |
| 2026-07-31 | 2026-Q2 | effective tax rate YTD 2026 | 18.4% | 34 |
| 2026-07-31 | 2026-Q2 | effective tax rate YTD 2025 | 25.1% | 34 |
| 2026-07-31 | 2026-Q2 | effective tax rate Q2 2026 | 20.5% | 34 |
| 2026-07-31 | 2026-Q2 | effective tax rate Q2 2025 | 23.4% | 34 |
| 2026-07-31 | 2026-Q2 | contingent consideration liability GRAIL | $40 | 34 |
| 2026-07-31 | 2026-Q2 | cash and cash equivalents | $1,040 | 34 |
| 2026-07-31 | 2026-Q2 | 2026 repurchase program remaining | $1.5 | 34 |
| 2026-07-31 | 2026-Q2 | 2024 repurchase program remaining | $279 | 34 |
| 2026-07-30 | 2026-Q2 | short-term investments | 128 (USD millions) | 33 |
| 2026-07-30 | 2026-Q2 | cash flow from operating activities | $201 | 33 |
| 2026-07-30 | 2026-Q2 | Cash and cash equivalents | $1,040 | 33 |
| 2026-07-30 | 2026-Q2 | Capital expenditures | $39 | 33 |
| 2026-05-04 | 2026-Q1 | short-term investments | $66 million | 32 |
| 2026-05-04 | 2026-Q1 | Operating margin | 19.2% | 32 |
| 2026-05-04 | 2026-Q1 | Gross margin | 66.1% | 32 |
| 2026-05-04 | 2026-Q1 | Effective tax rate | 14.8% | 32 |
| 2026-05-04 | 2026-Q1 | Cash and cash equivalents | $1,089 million | 32 |
| 2026-04-30 | 2026-Q1 | Cash and short-term investments | $1.16 billion | 31 |
| 2026-04-30 | 2026-Q1 | Cash and cash equivalents | $1,089 | 31 |
| 2026-02-12 | FY2025 | Voluntary turnover rate | 8% | 30 |
| 2026-02-12 | FY2025 | short-term investments | 215 million | 30 |
| 2026-02-12 | FY2025 | Foreign subsidiaries cash | 444 million | 30 |
| 2026-02-12 | FY2025 | Cash and equivalents | 1,418 million | 30 |
| 2026-02-12 | FY2025 | R&D expense | $967 million | 30 |
| 2026-02-12 | FY2025 | Pending patent applications outside the U.S. | 4,218 | 30 |
| 2026-02-12 | FY2025 | Pending U.S. patent applications | 1,120 | 30 |
| 2026-02-12 | FY2025 | Issued patents outside the U.S. | 7,653 | 30 |
| 2026-02-12 | FY2025 | Issued U.S. patents | 1,380 | 30 |
| 2026-02-12 | FY2025 | Backlog to be shipped in 2027 | 13% | 30 |
| 2026-02-12 | FY2025 | Backlog to be shipped in 2026 | 77% | 30 |
| 2026-02-12 | FY2025 | Backlog | $738 million | 30 |
| 2026-01-13 | FY2025 | Ex-China revenue (Q4 2025) | approximately $1.100 billion | 28 |
| 2026-01-13 | FY2025 | Ex-China revenue (FY2025) | approximately $4.10 billion | 28 |
| 2026-02-05 | 2025-Q4 | short-term investments | $215 million | 29 |
| 2026-02-05 | 2025-Q4 | Cash and cash equivalents | $1,418 million | 29 |
| 2025-10-31 | 2025-Q3 | Total cash equivalents and investments | 1,278 (USD millions) | 27 |
| 2025-10-31 | 2025-Q3 | short-term investments | 228 (USD millions) | 27 |
| 2025-10-31 | 2025-Q3 | share repurchase authorization available | 684 | 27 |
| 2025-10-31 | 2025-Q3 | GRAIL contingent consideration liability | 43 | 27 |
| 2025-10-31 | 2025-Q3 | Foreign subsidiaries cash | 501 (USD millions) | 27 |
| 2025-10-31 | 2025-Q3 | cash and cash equivalents | 1,050 (USD millions) | 27 |
| 2025-10-30 | 2025-Q3 | total cash and investments | $1,280 | 26 |
| 2025-10-30 | 2025-Q3 | short-term investments | $228 | 26 |
| 2025-10-30 | 2025-Q3 | Cash and equivalents | $1,050 | 26 |
| 2025-07-31 | 2025-Q2 | short-term investments | $221 | 24 |
| 2025-07-31 | 2025-Q2 | Operating cash flow | $234 | 24 |
| 2025-07-31 | 2025-Q2 | Cash and cash equivalents | $934 | 24 |
| 2025-05-09 | 2025-Q1 | taxes paid net share settlement | $22 | 23 |
| 2025-05-09 | 2025-Q1 | strategic investments purchased | $24 | 23 |
| 2025-05-09 | 2025-Q1 | stock repurchased | $200 | 23 |
| 2025-05-09 | 2025-Q1 | short-term investments | $124 | 23 |
| 2025-05-09 | 2025-Q1 | share repurchase remaining available | $1.2 | 23 |
| 2025-05-09 | 2025-Q1 | share repurchase authorization | $1.5 | 23 |
| 2025-05-09 | 2025-Q1 | share-based compensation expense | $73 | 23 |
| 2025-05-09 | 2025-Q1 | revolving credit facility | $750 | 23 |
| 2025-05-09 | 2025-Q1 | gross margin core Illumina | 65.6% | 23 |
| 2025-05-09 | 2025-Q1 | gross margin consolidated | 65.6% | 23 |
| 2025-05-09 | 2025-Q1 | Greater China region revenue 2024 | $308 | 23 |
| 2025-05-09 | 2025-Q1 | estimated tariff cost impact | $85 | 23 |
| 2025-05-09 | 2025-Q1 | depreciation and amortization expense | $69 | 23 |
| 2025-05-09 | 2025-Q1 | covered revenues Q4 2024 | $38 | 23 |
| 2025-05-09 | 2025-Q1 | covered revenue payments paid Q1 2025 | $360,000 | 23 |
| 2025-05-09 | 2025-Q1 | contingent consideration long-term liabilities | $59 | 23 |
| 2025-05-09 | 2025-Q1 | contingent consideration liability related to GRAIL | $61 | 23 |
| 2025-05-09 | 2025-Q1 | cash held by foreign subsidiaries | $432 | 23 |
| 2025-05-09 | 2025-Q1 | cash and cash equivalents and short-term investments | $1,237 | 23 |
| 2025-05-09 | 2025-Q1 | cash and cash equivalents | $1,113 | 23 |
| 2025-05-09 | 2025-Q1 | capital expenditures | $32 | 23 |
| 2025-05-09 | 2025-Q1 | capital commitments callable recallable distributions | $10 | 23 |
| 2025-05-09 | 2025-Q1 | capital commitments callable | $3 | 23 |
| 2025-05-09 | 2025-Q1 | 2031 Term Notes principal | $500 | 23 |
| 2025-05-09 | 2025-Q1 | 2031 Term Notes interest rate | 2.550% | 23 |
| 2025-05-09 | 2025-Q1 | 2027 Term Notes principal | $500 | 23 |
| 2025-05-09 | 2025-Q1 | 2027 Term Notes interest rate | 5.750% | 23 |
| 2025-05-09 | 2025-Q1 | 2026 Term Notes principal | $500 | 23 |
| 2025-05-09 | 2025-Q1 | 2026 Term Notes interest rate | 4.650% | 23 |
| 2025-05-09 | 2025-Q1 | 2025 Term Notes principal | $500 | 23 |
| 2025-05-09 | 2025-Q1 | 2025 Term Notes interest rate | 5.800% | 23 |
| 2025-05-08 | 2025-Q1 | tariff related costs | $85 million | 22 |
| 2025-05-08 | 2025-Q1 | short-term investments | $124 | 22 |
| 2025-05-08 | 2025-Q1 | cash, cash equivalents and short-term investments | $1.24 billion | 22 |
| 2025-05-08 | 2025-Q1 | Cash and cash equivalents | $1,113 | 22 |
| 2025-02-12 | FY2024 | short-term investments | $93 million | 21 |
| 2025-02-12 | FY2024 | Cash and cash equivalents | $1,127 million | 21 |
| 2025-02-12 | FY2024 | Backlog | $657 million | 21 |
| 2025-02-06 | 2024-Q4 | term debt | $1,989 | 20 |
| 2025-02-06 | 2024-Q4 | stockholders equity | $2,373 | 20 |
| 2025-02-06 | 2024-Q4 | short-term investments | $93 | 20 |
| 2025-02-06 | 2024-Q4 | Cash and cash equivalents | $1,127 | 20 |
| 2024-11-06 | 2024-Q3 | short-term investments | 70 (USD millions) | 18 |
| 2024-11-06 | 2024-Q3 | GRAIL contingent consideration liability | 82 | 18 |
| 2024-11-06 | 2024-Q3 | foreign subsidiary cash | 464 (USD millions) | 18 |
| 2024-11-06 | 2024-Q3 | cash and cash equivalents | 869 (USD millions) | 18 |
| 2024-11-04 | 2024-Q3 | term debt | $1,988 | 17 |
| 2024-11-04 | 2024-Q3 | stockholders' equity | $2,125 | 17 |
| 2024-11-04 | 2024-Q3 | short-term investments | $70 | 17 |
| 2024-11-04 | 2024-Q3 | Cash and cash equivalents | $869 | 17 |
| 2024-08-07 | 2024-Q2 | stock repurchase authorization remaining | 15 | 16 |
| 2024-08-07 | 2024-Q2 | short-term investments (as of June 30, 2024) | 74 (USD millions) | 16 |
| 2024-08-07 | 2024-Q2 | revolving credit facility amount available | 750 (USD millions) | 16 |
| 2024-08-07 | 2024-Q2 | Fair value of contingent consideration liability (GRAIL CVRs) | 131 | 16 |
| 2024-08-07 | 2024-Q2 | European Commission fine accrued | 481 | 16 |
| 2024-08-07 | 2024-Q2 | Delayed Draw Credit Facility amount borrowed | 750 (USD millions) | 16 |
| 2024-08-07 | 2024-Q2 | Cash and cash equivalents (as of June 30, 2024) | 920 (USD millions) | 16 |
| 2024-08-06 | 2024-Q2 | Cash and equivalents | $994 | 15 |
| 2024-05-03 | 2024-Q1 | Term Notes 2031 | 500 | 14 |
| 2024-05-03 | 2024-Q1 | Term Notes 2027 | 500 | 14 |
| 2024-05-03 | 2024-Q1 | Term Notes 2025 | 500 | 14 |
| 2024-05-03 | 2024-Q1 | short-term investments | 7 (USD millions) | 14 |
| 2024-05-03 | 2024-Q1 | Share-based compensation expense | 96 | 14 |
| 2024-05-03 | 2024-Q1 | Share repurchase authorization remaining | 15 | 14 |
| 2024-05-03 | 2024-Q1 | Restructuring charges | 36 | 14 |
| 2024-05-03 | 2024-Q1 | Property and equipment impairment | 32 | 14 |
| 2024-05-03 | 2024-Q1 | Gross margin Core Illumina | 65.7% | 14 |
| 2024-05-03 | 2024-Q1 | GRAIL performance-based award potential value | 78 (USD millions) | 14 |
| 2024-05-03 | 2024-Q1 | GRAIL cash incentive awards unvested | 279 (USD millions) | 14 |
| 2024-05-03 | 2024-Q1 | Foreign subsidiary cash | 614 (USD millions) | 14 |
| 2024-05-03 | 2024-Q1 | European Commission fine accrued | 478 | 14 |
| 2024-05-03 | 2024-Q1 | Effective tax rate | (15.3)% | 14 |
| 2024-05-03 | 2024-Q1 | Depreciation and amortization | 108 | 14 |
| 2024-05-03 | 2024-Q1 | Credit Facility | 750 | 14 |
| 2024-05-03 | 2024-Q1 | Covered Revenues Q1 2024 expected | 27 (USD millions) | 14 |
| 2024-05-03 | 2024-Q1 | Covered Revenue Payments Q2 2024 expected | 250 (USD thousands) | 14 |
| 2024-05-03 | 2024-Q1 | Contingent consideration liability GRAIL | 403 | 14 |
| 2024-05-03 | 2024-Q1 | Consolidated gross margin | 62.0% | 14 |
| 2024-05-03 | 2024-Q1 | Cash and cash equivalents | 1108 (USD millions) | 14 |
| 2024-05-03 | 2024-Q1 | Capital expenditures | 36 (USD millions) | 14 |
| 2024-05-03 | 2024-Q1 | Accrued GRAIL awards liability | 41 | 14 |
| 2024-05-02 | 2024-Q1 | Purchases of property and equipment | $(36) | 13 |
| 2024-05-02 | 2024-Q1 | GRAIL revenue | $27 | 13 |
| 2024-05-02 | 2024-Q1 | Depreciation and amortization expenses | $108 | 13 |
| 2024-05-02 | 2024-Q1 | Core Illumina revenue | $1,056 | 13 |
| 2024-05-02 | 2024-Q1 | Cash flow provided by operating activities | $77 | 13 |
| 2024-05-02 | 2024-Q1 | Cash and cash equivalents | $1,108 | 13 |
| 2024-02-16 | FY2023 | Women percentage GRAIL | 55% | 12 |
| 2024-02-16 | FY2023 | Women percentage Core Illumina | 45% | 12 |
| 2024-02-16 | FY2023 | Voluntary turnover rate GRAIL | 8% | 12 |
| 2024-02-16 | FY2023 | Voluntary turnover rate Core Illumina | 7% | 12 |
| 2024-02-16 | FY2023 | US minorities percentage Core Illumina | 54% | 12 |
| 2024-02-16 | FY2023 | Operating cash flow 2023 | 478 million | 12 |
| 2024-02-16 | FY2023 | Operating cash flow 2022 | 392 million | 12 |
| 2024-02-16 | FY2023 | Operating cash flow 2021 | 545 million | 12 |
| 2024-02-16 | FY2023 | GRAIL contingent workers | 380 | 12 |
| 2024-02-16 | FY2023 | European Commission fine accrual | 484 million | 12 |
| 2024-02-16 | FY2023 | Credit facility amount | 750 million | 12 |
| 2024-02-16 | FY2023 | Core Illumina contingent workers | 1,370 | 12 |
| 2024-02-16 | FY2023 | contingent consideration liability GRAIL | 387 million | 12 |
| 2024-02-16 | FY2023 | cash and cash equivalents | 1,048 million | 12 |
| 2024-02-16 | FY2023 | 2031 term notes principal | 500 million | 12 |
| 2024-02-16 | FY2023 | 2027 term notes principal | 500 million | 12 |
| 2024-02-16 | FY2023 | 2025 term notes principal | 500 million | 12 |
| 2024-02-08 | 2023-Q4 | short-term investments | 6 (USD millions) | 11 |
| 2024-02-08 | 2023-Q4 | Cash and cash equivalents | 1,048 (USD millions) | 11 |
| 2024-01-09 | 2023-Q4 | Core Illumina revenue Q4 2023 | approximately $1,090 million | 10 |
| 2024-01-09 | 2023-Q4 | Core Illumina revenue Fiscal Year 2023 | approximately $4,431 million | 10 |
| 2024-01-09 | 2023-Q4 | Core Illumina GAAP operating margin Q4 2023 | 2.4% | 10 |
| 2024-01-09 | 2023-Q4 | Core Illumina GAAP operating margin Fiscal Year 2023 | 12.3% | 10 |
| 2024-01-09 | 2023-Q4 | Consolidated revenue Q4 2023 | approximately $1,115 million | 10 |
| 2024-01-09 | 2023-Q4 | Consolidated revenue Fiscal Year 2023 | approximately $4,497 million | 10 |
| 2024-01-09 | 2023-Q4 | Consolidated GAAP operating margin Q4 2023 | (15.5)% | 10 |
| 2024-01-09 | 2023-Q4 | Consolidated GAAP operating margin Fiscal Year 2023 | (24.0)% | 10 |
| 2023-11-13 | 2023-Q3 | short-term investments | 6 (USD millions) | 9 |
| 2023-11-13 | 2023-Q3 | Cash and equivalents | 933 (USD millions) | 9 |
| 2023-11-09 | 2023-Q3 | NovaSeq X instruments expected FY2023 | 330 to 340 | 8 |
| 2023-11-09 | 2023-Q3 | Cash and equivalents | $933 | 8 |
| 2023-08-10 | 2023-Q2 | Operating loss | -152 million | 7 |
| 2023-08-10 | 2023-Q2 | Net loss YTD | -231 million | 7 |
| 2023-08-10 | 2023-Q2 | gross margin core Illumina | 65.5% | 7 |
| 2023-08-10 | 2023-Q2 | gross margin consolidated | 62.2% | 7 |
| 2023-08-10 | 2023-Q2 | foreign subsidiary cash | 413 million | 7 |
| 2023-08-10 | 2023-Q2 | European Commission fine accrued | 471 million | 7 |
| 2023-08-10 | 2023-Q2 | contingent consideration liability GRAIL | 440 million | 7 |
| 2023-08-10 | 2023-Q2 | Cash and equivalents | 1.6 billion | 7 |
| 2023-08-09 | 2023-Q2 | short-term investments | $6 | 6 |
| 2023-08-09 | 2023-Q2 | NovaSeq X supply capacity | more than 390 | 6 |
| 2023-08-09 | 2023-Q2 | NovaSeq X shipments | 109 | 6 |
| 2023-08-09 | 2023-Q2 | Cash and cash equivalents | $1,553 | 6 |
| 2023-05-05 | 2023-Q1 | Expected covered revenues Q1 2023 | approximately 19 | 5 |
| 2023-05-05 | 2023-Q1 | Expected covered revenue payments Q2 2023 | approximately 183,000 | 5 |
| 2023-05-05 | 2023-Q1 | Effective tax rate Q1 2023 | 103.9% | 5 |
| 2023-05-05 | 2023-Q1 | Effective tax rate Q1 2022 | 38.3% | 5 |
| 2023-05-05 | 2023-Q1 | covered revenues Q4 2022 | 23 (USD millions) | 5 |
| 2023-05-05 | 2023-Q1 | covered revenue payments Q1 2023 | 217,000 (USD millions) | 5 |
| 2023-04-25 | 2023-Q1 | short-term investments | 24 (USD in millions) | 4 |
| 2023-04-25 | 2023-Q1 | Operating cash flow | 10 (USD in millions) | 4 |
| 2023-04-25 | 2023-Q1 | NovaSeq X order book quarter-end | over 200 | 4 |
| 2023-04-25 | 2023-Q1 | Depreciation and amortization expenses | 107 (USD in millions) | 4 |
| 2023-04-25 | 2023-Q1 | Cash and cash equivalents | 1,494 (USD in millions) | 4 |
| 2023-04-25 | 2023-Q1 | Capital expenditures | 52 (USD in millions) | 4 |
| 2023-04-25 | 2023-Q1 | Annualized run rate cost savings commitment | more than $100 million | 4 |
Guidance Tracking (latest per metric/period · 17/31)#
All management forecasts (guidance) and their later outcome. Types: fiscal-year targets as well as quarterly/half-year targets; per metric and period the most recent statement applies, older versions can be expanded. The status is checked automatically against the actuals reported later: open (period still running), met, beaten, missed. For ranges (“X to Y”) reaching the range counts. Logged neutrally, no estimate of our own, no assessment.
Actuals: revenue in $m · EPS in $ per share · ratios in %
| For period | Guided on | Metric | Guided | Actual | Verdict | Direction | Source |
|---|---|---|---|---|---|---|---|
| FY2026 | 2026-07-30 | EPS (non-GAAP) | 5.3–5.4 | – | pending | raised | 33 |
| FY2026 | 2026-07-30 | ROW organic revenue growth | 5% | – | pending | raised | 33 |
| FY2026 | 2026-04-30 | Revenue | 4,600–4,640 | – | pending | raised | 33 |
| FY2026 | 2026-04-30 | Operating margin | 23.4%-23.6% | – | pending | confirmed | 33 |
| FY2026 | 2026-04-30 | Revenue growth (YoY) | -6–4% | – | pending | confirmed | 31 |
| FY2026 | 2026-02-05 | Total company revenue | 4,500–4,600 | – | pending | initiated | 29 |
| FY2026 | 2026-02-05 | Ex-China organic revenue growth | 2–4% | – | pending | initiated | 29 |
| FY2025 | 2026-01-13 ° | EPS (GAAP) | 5.42–5.45 | 5.45 | in line | confirmed | 28 |
| FY2025 | 2026-01-13 ° | EPS (non-GAAP) | 4.76–4.79 | 4.84 | beat | confirmed | 28 |
| FY2025 | 2025-10-30 | Revenue growth (YoY) | 0.5–1.5% | – | – | raised | 26 |
| FY2025 | 2025-10-30 | Revenue ex-China | 0.5–1.5% | – | – | confirmed | 26 |
| FY2025 | 2025-07-31 | Constant currency revenue | 0.5–2.5% | – | – | raised | 24 |
| FY2025 | 2025-05-08 | Core Illumina revenue | 1–3% | – | – | cut | 22 |
| FY2025 | 2025-05-08 | Revenue outside of the Greater China region | 0–2% | – | – | confirmed | 22 |
| FY2025 | 2025-05-08 | Reported revenue from the Greater China region | 165–185 | – | – | confirmed | 22 |
| FY2025 | 2025-01-14 | Revenue | ~4,340 | 4,343 | beat | confirmed | 28 |
| FY2025 | 2025-01-14 | Operating margin | 22.75–23% | 18.6 | miss | raised | 26 |
| FY2024 | 2024-11-04 | EPS (non-GAAP) | 4.05–4.15 | 4.16 | beat | raised | 17 |
| FY2024 | 2024-11-04 | Operating margin | 21–21.5% | -19.1 | miss | raised | 17 |
| FY2024 | 2024-11-04 | Core Illumina revenue | ~3% | – | – | cut | 17 |
| 2024-Q4 | 2024-11-04 | Core Illumina revenue | ~1,070 | – | – | initiated | 17 |
| FY2023 | 2023-11-09 | EPS (non-GAAP) | 0.6–0.7 | 0.86 | beat | – | 8 |
| FY2023 | 2023-11-09 | Revenue growth (YoY) | 2–3% | – | – | cut | 8 |
| FY2023 | 2023-11-09 | Core Illumina revenue | 3–4% | – | – | cut | 8 |
| FY2023 | 2023-11-09 | GAAP diluted loss per share | -6.67–-6.57 | – | – | – | 8 |
| FY2023 | 2023-04-25 | GRAIL revenue | 90–110 | – | – | – | 8 |
| FY2023 | 2023-02-07 | EPS (GAAP) | 0.03–0.28 | -7.34 | – | initiated | 2 |
| FY2023 | 2023-01-11 | Operating margin | ~22% | -23.7 | miss | confirmed | 1 |
| FY2023 | 2023-01-11 | Core Illumina revenue growth | 6–9% | – | – | confirmed | 4 |
| FY2023 | 2023-01-11 | GRAIL revenue growth | ~80% | – | – | confirmed | 1 |
| FY2023 | 2023-01-11 | GRAIL operating loss | ~670 | – | – | confirmed | 1 |
Development#
A condensed summary per reporting period as running text: what changed operationally, which drivers management names, how earnings and cash flow developed. Most recent period first, grouped by year; each text is written from the original report of that period, superscript numbers lead to the source.
FY2026
In fiscal year 2026, Illumina reported revenue of $1.09 billion in Q1 and $1.16 billion in Q2, representing year-over-year growth of 4.8% and 9.5% respectively, driven primarily by increased demand for NovaSeq X high-throughput consumables and instruments 31 33. The company completed the acquisition of SomaLogic on January 30, 2026 for $460 million, expanding its presence in the proteomics market as part of a multiomics strategy 32. GAAP operating margin expanded on a year-to-date basis to 20.2% from 18.0% in the prior-year period, though year-to-date gross margin improvement from 65.6% to 66.2% was partly attributable to a $23 million intangible asset impairment recorded in Q2 2025 34. Management raised full-year revenue guidance twice during the first half, from an initial range of $4.52-$4.62 billion to $4.60-$4.64 billion by the end of Q2, while non-GAAP diluted EPS guidance was raised to $5.30-$5.40 31 33. Greater China revenue declined approximately $20 million year-over-year in Q1 following the company's inclusion on China's Unreliable Entities List, with tariff uncertainty cited as an ongoing risk heading into the second half 32 33.
FY2025
Illumina reported FY2025 revenue of $4,343 million, flat versus 2024 on both a reported and constant currency basis, with ex-China revenue of $4.10 billion up 2% as a $65 million decrease in Greater China revenue resulted from the company's addition to China's Unreliable Entities List and a sequencing instrument export prohibition enacted in early 2025 29 30. GAAP operating income was $807 million and non-GAAP operating income was $1,004 million, with full-year GAAP operating margin of 18.6% and non-GAAP operating margin of 23.1% 29. GAAP diluted EPS of $5.45 and non-GAAP diluted EPS of $4.84 were supported by free cash flow of $931 million and cash growth to $1,418 million by year-end 129. Revenue trends improved progressively over the course of the year, from reported declines in Q1 and Q2 to flat in Q3 and 5% growth in Q4 2025 on a reported basis 29. Material events for the year included an incremental $100 million cost reduction program and the signing and subsequent completion of the acquisition of the SomaLogic business from Standard BioTools for $350 million in cash, closed January 30, 2026 22 30.
FY2024
Illumina's fiscal year 2024 consolidated revenue declined approximately 3% to $4,372 million, as growth in sequencing consumables was more than offset by weaker sequencing instruments demand across all four quarters (21, 129). The defining corporate event was the completion of the GRAIL spin-off on June 24, 2024, which distributed approximately 85.5% of GRAIL shares to stockholders and triggered $1,889 million in goodwill and intangible impairment charges, producing a GAAP net loss of $1,223 million for the full year (21, 16, 129). Excluding these non-cash charges, adjusted operating income reached $922 million and adjusted diluted EPS was $4.16, with the Core Illumina non-GAAP operating margin expanding to 21.3% for FY2024 (129, 20). Full-year gross margin widened to 65.4% from 60.9% in 2023, driven by a favorable mix shift toward sequencing consumables and operational excellence cost reductions (21). In September 2024 the European Commission withdrew its previously imposed €432 million fine, resulting in a $481 million recognized gain, and free cash flow for the year totaled $709 million (18, 21, 129).
FY2023
Illumina's fiscal 2023 revenue declined 2% to $4,504 million, driven primarily by lower sequencing consumables and instruments sales as the NovaSeq X platform launch continued to compress gross margin to 60.9% from 64.8% in the prior year 12. The GAAP operating loss of $(1,069) million improved from $(4,218) million in FY2022, but that improvement reflects a $3.1 billion reduction in goodwill and intangible impairment charges rather than underlying operational gains; Core Illumina non-GAAP operating margin was 19.8% and non-GAAP diluted EPS declined to $0.86 from $2.12 in FY2022 10 11 12. The company shipped 352 NovaSeq X instruments in fiscal 2023 and launched the XLEAP-SBS sequencing chemistry, extending per-genome cost reduction 11 12. The European Commission imposed a €432 million fine in July 2023 for completion of the GRAIL acquisition, and in December 2023 Illumina announced plans to divest GRAIL through a third-party sale or capital markets transaction targeting finalization by end of Q2 2024 12. Full-year free cash flow was $283 million compared to $106 million in FY2022, with $1,048 million in cash and net debt of $441 million at year-end 11 120.
Sources: official investor relations documents#
All original documents used, with type (e.g. quarterly, half-year, annual report), publication date and a direct link to the filing (EDINET/SEC/IR). Every superscript number in the report points to an entry in this list; so every figure can be traced back to its place in the original.
| # | Document type | Published | Link |
|---|---|---|---|
| #1 | 8-K-EX99.1 | 2023-01-11 | Open |
| #2 / #102 | 8-K-EX99.1 | 2023-02-07 | Open |
| #3 | 10-K | 2023-02-17 | Open |
| #4 / #104 | 8-K-EX99.1 | 2023-04-25 | Open |
| #5 | 10-Q | 2023-05-05 | Open |
| #6 / #106 | 8-K-EX99.1 | 2023-08-09 | Open |
| #7 | 10-Q | 2023-08-10 | Open |
| #8 / #108 | 8-K-EX99.1 | 2023-11-09 | Open |
| #9 | 10-Q | 2023-11-13 | Open |
| #10 | 8-K-EX99.1 | 2024-01-09 | Open |
| #11 / #111 | 8-K-EX99.1 | 2024-02-08 | Open |
| #12 | 10-K | 2024-02-16 | Open |
| #13 / #113 | 8-K-EX99.1 | 2024-05-02 | Open |
| #14 | 10-Q | 2024-05-03 | Open |
| #15 / #115 | 8-K-EX99.1 | 2024-08-06 | Open |
| #16 | 10-Q | 2024-08-07 | Open |
| #17 / #117 | 8-K-EX99.1 | 2024-11-04 | Open |
| #18 | 10-Q | 2024-11-06 | Open |
| #19 / #119 | 8-K-EX99.1 | 2025-01-14 | Open |
| #20 / #120 | 8-K-EX99.1 | 2025-02-06 | Open |
| #21 | 10-K | 2025-02-12 | Open |
| #22 / #122 | 8-K-EX99.1 | 2025-05-08 | Open |
| #23 | 10-Q | 2025-05-09 | Open |
| #24 / #124 | 8-K-EX99.1 | 2025-07-31 | Open |
| #25 | 10-Q | 2025-08-01 | Open |
| #26 / #126 | 8-K-EX99.1 | 2025-10-30 | Open |
| #27 | 10-Q | 2025-10-31 | Open |
| #28 | 8-K-EX99.1 | 2026-01-13 | Open |
| #29 / #129 | 8-K-EX99.1 | 2026-02-05 | Open |
| #30 | 10-K | 2026-02-12 | Open |
| #31 / #131 | 8-K-EX99.1 | 2026-04-30 | Open |
| #32 | 10-Q | 2026-05-04 | Open |
| #33 / #133 | 8-K-EX99.1 | 2026-07-30 | Open |
| #34 | 10-Q | 2026-07-31 | Open |
Older sources (+19)
| # | Document type | Published | Link |
|---|---|---|---|
| #201 | 10-K | 2016-03-02 | Open |
| #204 | 10-K | 2016-03-02 | Open |
| #206 | 10-K | 2016-03-02 | Open |
| #202 | 10-Q | 2016-05-09 | Open |
| #203 | 10-Q | 2016-08-02 | Open |
| #205 | 10-Q | 2017-08-03 | Open |
| #208 | 10-K | 2018-02-13 | Open |
| #207 | 10-Q | 2018-07-31 | Open |
| #212 | 10-K | 2019-02-12 | Open |
| #209 | 10-Q | 2019-04-26 | Open |
| #210 | 10-Q | 2019-07-31 | Open |
| #211 | 10-Q | 2019-10-25 | Open |
| #216 | 10-K | 2020-02-11 | Open |
| #213 | 10-Q | 2020-05-01 | Open |
| #214 | 10-Q | 2020-08-07 | Open |
| #215 | 10-Q | 2020-10-30 | Open |
| #217 | 10-Q | 2021-04-28 | Open |
| #218 | 10-Q | 2021-08-06 | Open |
| #219 | 10-Q | 2021-11-05 | Open |
FAQ#
Is there a management forecast (guidance) for FY2026?
Yes. Management has issued targets for FY2026, including EPS (non-GAAP). The guidance tracking chapter shows all targets and checks them against the actuals reported later; neutral, with no estimate of our own.
Where can I find the official investor relations documents of Illumina Inc.?
The sources chapter links all 69 original filings used (SEC filings) with type, publication date and a direct link; every figure in the report carries a source number.